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Gastroenterology

News, opinions and meeting coverage in gastroenterology.

FDA Rejects NK1R Antagonist for Gastroparesis

— Drugmaker none-too-pleased with agency's request for additional studies

FDA CRL tradipitant (Vanda) over a computer rendering of a stomach.

Latest in Gastroenterology

GLP-1 Drugs in MASLD Tied to Lower Risk of Cirrhosis, Death

Limited benefit seen in patients with established cirrhosis, however

Sep 16, 2024
Another Possible Treatment Option for Intermediate-Stage Liver Cancer

Adding lenvatinib, pembrolizumab to TACE significantly improved PFS, numerically improved OS

Sep 16, 2024
Approved Liver Disease Drug Has No Clinical Benefit, FDA Panel Says

Agency advisors put their foot down on shaky science for Ocaliva in primary biliary cholangitis

Sep 13, 2024
HHS Proposes Rule to Increase Access to Kidney, Liver Transplants in HIV Patients

Rule would streamline criteria for organ donation from donors with HIV to recipients with HIV

Sep 13, 2024
Approved Liver Disease Drug Has No Clinical Benefit, FDA Panel Says

Agency advisors put their foot down on shaky science for Ocaliva in primary biliary cholangitis

HHS Proposes Rule to Increase Access to Kidney, Liver Transplants in HIV Patients

Rule would streamline criteria for organ donation from donors with HIV to recipients with HIV

Gastroenterology Case Studies

Child Develops Voluminous Diarrhea After Amoxicillin

Discordant test results complicate diagnosis of suspected C. difficile

 A photo of a fecal sample container.
Elderly Farmer Experiences Strange Abdominal Rash and GI Symptoms

Moral of the story: don't walk barefoot in the fields

A photo of a senior woman laying in bed grimacing and holding her stomach.
Case Shows Danger of Gallstone Ileus in Patients Over 65

Clinicians found CT scan to be best diagnostic tool

 A photo of a senior woman outdoors doubled over in pain.

More in Gastroenterology

FDA Warning on Hot Flash Drug

Clinicians should perform liver blood tests before and during Veozah treatment

Sep 12, 2024
FDA WARNING fezolinetant (Veozah) over a photo of Veozah tablet, bottle and packaging.
FDA Expands Approval of IL-23 Drug to Ulcerative Colitis

In trials, guselkumab more than doubled remission rates versus placebo

Sep 12, 2024
FDA approved guselkumab (Tremfya) over a computer rendering of ulcerative colitis.
FDA Reviewers Skeptical of Ocaliva for Rare Bile Duct Disease

Agency advisory panel to examine complicated efficacy data and liver safety concerns

Sep 11, 2024
FDA ADCOMM obeticholic acid (Ocaliva) over a computer rendering of a liver with the biliary tree highlighted.
Thanks to Reddit, a New Diagnosis Is Bubbling Up Across the Nation

Botox can help "no-burp syndrome" symptoms

Sep 11, 2024
A photo of a person holding a smartphone which is displaying the Reddit logo.
Comparing Fecal Immunochemical Tests; CVD Blood Test for Women

Also in TTHealthWatch: beta-blockers after MI

Sep 07, 2024
TTUHSC EL PASO HEALTHWATCH with their logo and photos of Rick Lange, MD, and Elizabeth Tracey
Upper GI Damage Tied to Subsequent Parkinson's Disease

Mucosal damage seen on upper endoscopy associated with 76% higher Parkinson's risk

Sep 06, 2024
 An xray image of the esophagus illuminated by a barium swallow.
Should Intensified Infliximab for Refractory Acute Severe UC Be Nixed?

PREDICT-UC trial found no benefit with intensified or accelerated regimens

Sep 06, 2024
A computer rendering of monoclonal antibody treatment of ulcerative colitis.
Study Backs Skipping 5-FU Bolus in Chemo Regimens for Gastrointestinal Cancers

No difference in overall survival with versus without bolus, less toxicity without

Sep 05, 2024
A close up photo of a nurse adjusting the flow rate of an intravenous infusion.
Women With HCC Less Likely to Receive Liver Transplant, More Likely to Die Than Men

This difference is mostly explained by their smaller stature, researchers say

Sep 05, 2024
 A photo of surgeons performing a liver transplant.
The Higher the Disability Burden From Disease, the Higher the Suicide Risk

Having a medical condition was tied to increased risk of suicide in a dose-response-like manner

Sep 04, 2024
A photo of a radiologist monitoring a computer as a female nurse observes a patient during MRI.
Novel Drug Reduced Triglycerides, Risk of Pancreatitis in Persistent Chylomicronemia

Benefits seen in patients with and without a genetic diagnosis

Sep 03, 2024
ESC over a photo of ExCeL London conference and exhibition center.
Another Injectable Toxoid Vaccine Flops for C. Diff

It's time to look at oral vaccines to prevent C. difficile infections, experts say

Aug 28, 2024
An electron micrograph of Clostridioides difficile bacteria
Rate of Mortality After ED Discharge for Cirrhosis Doubles That of Heart Failure

Patients who lacked a follow-up visit may be at particularly high risk for death

Aug 28, 2024
 A computer rendering of a transparent body with the liver highlighted in red.
Opinion
Olympic Chief Medical Officer on Athletes' GI Illness After Seine Events

IOC data show "about a 10% infection rate in those who swam in the Seine"

Aug 28, 2024
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