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News, opinions and meeting coverage in gastroenterology.

Onco Break over a computer rendering of a cancer cell.

A First in Total Larynx Transplant; 'Sniffing' Out Lung Cancer; Gen X Cancer Toll

News, features, and commentary about cancer-related issues

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Neuromuscular Training Decreased Incidence of Chemo-Induced Peripheral Neuropathy

Incidence significantly reduced with two types of exercises versus usual care

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Court: Some Employers Can Exclude PrEP, Cancer Screenings From Insurance Coverage

Not all preventive care recommended by the USPSTF is threatened by the narrow ruling, however

FDA APPROVED adagrasib (Krazati) over a computer rendering of colorectal cancer.

Adagrasib Wins Accelerated Approval for KRAS-Mutant Colorectal Cancer

KRAS inhibitor plus cetuximab achieved 34% response rate, 85% disease control in early trial

ASCO over a photo of McCormick Place in Chicago, IL

A Win for Liver Transplantation in Unresectable Metastatic Colorectal Cancer

Three new trials address CRC liver metastases

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Increase in CRC Cases in Younger Age Groups Extends to Preteens

While cases remain rare in younger people, they're much more common than 25 years ago

A computer rendering of a colorectal tumor.

Blood in Stool, Abdominal Pain Top Red Flags for Early-Onset Colorectal Cancer

These symptoms are "frequently ignored by providers as trivial," according to one expert

FDA ADCOMM Blood-based colorectal cancer test (Shield) over a photo of the product.

Blood Test for Colon Cancer Screening Secures FDA Panel's Blessing

But advisors urge strong labeling emphasizing Shield test's low sensitivity for advanced adenomas

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Blood-Based Test for CRC Screening Hits Sensitivity, Specificity Endpoints

Test could fill a gap in CRC screening

A close up photo of methylphenidate tablets.

Psychostimulant No Help in Relieving Cancer-Related Fatigue

No significant differences in outcomes between methylphenidate, placebo

FDA ADCOMM Blood-based colorectal cancer test (Shield) over a photo of the product.

Blood Test for Colon Cancer Screening May Miss Some Precancers, FDA Staff Says

Shield could boost screening compliance, but has low sensitivity for advanced adenomas

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Patients Like AI for Endoscopy

But survey shows they still want a doctor in charge

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Pig-Kidney Recipient Dies; Colon Cancers Surge in Teens; CRISPR Fails to Cure HIV

Health news and commentary gathered by 妖姬直播 staff

A photo of a female physician holding a colonoscope.

Colonoscopy Near Time of Joint Replacement Doesn't Increase Infection Risk

However, several comorbidities, male sex may play a role

A computer rendering of a healthy colon.

It May Be Safe to Extend Time Between Colonoscopy Screenings, Study Says

Findings have implications for economics of resource use and avoiding invasive examinations

A photo of a physician pointing to a monitor image during a flexible sigmoidoscopy bowel cancer screening

Major Gaps in Cancer Screening at Federally Qualified Health Centers

Breast, cervical, colorectal cancer screening rates much lower than overall national rates

A photo of a vial and syringe of propofol.

Deeper Sedation During Colonoscopy Linked to Improved Detection of Serrated Polyps

Propofol boosts serrated polyp detection by 50%, little difference for all neoplasia, adenomas

A photo of a fecal immunochemical test kit.

Automated, Personalized Outreach Boosts CRC Screening in Diverse Patient Population

Absolute improvement of 30-40% in screening participation after 1 year

AACR over a photo of San Diego Convention Center in San Diego, CA

Possible New Standard for Treated Advanced CRC With KRAS Mutations

Adagrasib plus cetuximab leads to responses in one-third of patients, median OS of 15.9 months

FDA APPROVED trastuzumab deruxtecan (Enhertu) over a computer rendering of antibodies attacking cancer cells

Enhertu Gets Tumor-Agnostic FDA Approval for HER2-Positive Cancers

About half of patients responded, duration of response as long as 19 months in three trials

A computer rendering of an endoscope illuminating a polyp in the large intestine

How Old Is Too Old for Surveillance Colonoscopy?

Study suggested risks may outweigh benefits for some older patients

A computer rendering of cancer cells in a test tube of blood held by a blue rubber gloved hand

Liquid Biopsy for CRC Screening May Not Be Ready for Prime Time

Not as effective for catching cases or as cost-effective as available tests, modeling studies say

Delta-8 THC Use Common in Teens; New Drug-Coated Balloon for Blocked Stents

Also in TTHealthWatch: new screening methods for colorectal cancer

A computer rendering of tumors in the colon.

Noninvasive Screening Tests Show Promise for Catching Colorectal Cancer

Could these tests help to increase the number of people who undergo screening?

A photo of a young male physician in his office talking to his senior male patient

Knowing When to Start, Knowing When to Stop

Discussions about screening recommendations can be difficult, but they're worth having

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King Charles' Cancer Diagnosis Highlights Long Wait Times Across the Pond

Survival for common cancers in the U.K. consistently lags behind

A computer rendering of Helicobacter pylori bacterium.

More Evidence Linking H. Pylori Infection to Colorectal Cancer

Increased CRC incidence and mortality, significantly reduced by infection treatment

A photo of fecal occult blood sample containers at a testing lab

More Population-Based Evidence That Screening for CRC Reduces Risk of Cancer Death

Large Swedish study shows 14% reduction in long-term CRC mortality, 16% reduction in all deaths

A computer rendering of a cancer cell in the bloodstream.

Another COVID Toll: Over 134,000 Undiagnosed Cancers During Height of Pandemic

Diagnosis rates remained low throughout 2020, with mortality increase projected

A photo of an out of focus woman snapping a cigarette in half.

Smokers Who Quit and Stick With It See Greatest Reduction in Cancer Risk

Cessation at any age proved helpful for lowering cancer risk

A computer rendering of a colon.

Unfavorable Colon Cancer Trends in Young Adults Seen Across the Pond, Too

Rise in predicted CRC mortality among Europeans under 50 may be due to increasing obesity rates

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How Can Cancer Risk Be Cut in Communities Exposed to Toxins?

Group outlines plan to bring the latest testing and treatment to medically underserved minorities

GiCS over a photo of Moscone Convention Center West in San Francisco, CA

Liquid Biopsy Has Mixed Performance for Predicting Colon Cancer Outcomes

Adjuvant chemo fails to move needle on DNA clearance, but dynamics predictive of DFS

GiCS over a photo of Moscone Convention Center West in San Francisco, CA

Big PFS Improvement in Highly Mutated CRC With Dual Immunotherapy

Nivolumab/ipilimumab led to improvement in untreated MSI-H/dMMR disease versus chemo

A computer rendering of a T-cell killing a cancer cell.

Vaccine 'Promising' for Delaying Relapse in KRAS-Mutated Pancreatic Cancer, CRC

T-cell response linked to 86% reduced risk of relapse, death

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Homelessness Tied to Worse Cancer Outcomes Among Veterans

However, all-cause mortality rates in lung, colon cancer lower versus other healthcare settings

A photo of the word cure in a dictionary.

'Curable': A Case for Precision of Language

Patients need a clear description of their prognosis

A photo of a man holding a diabetes injection pen.

GLP-1 Drugs Linked to Lower Colorectal Cancer Risk for Diabetes Patients

Association strongest in patients with overweight, obesity

A photo of a woman pricking her finger.

Diabetes Linked to Higher Colorectal Cancer Risk

Associated risks highest in those with recent diagnoses

A photo of a male firefighter standing in front of a fire truck.

Moving Beyond the 'Angelina Jolie Effect' to Address Cancer Disparities

A "local heroes effect" can better reach communities of color

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