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Personalized Breast Cancer Treatment; Insights Into HPV in Men; Exercise and Cancer

— News, features, and commentary about cancer-related issues

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Onco Break over a computer rendering of a cancer cell.

Surgical innovations for breast cancer have led to that are more complex than lumpectomy versus mastectomy. (Mayo Clinic)

Using a breast cancer's to guide treatment showed promise for improving outcomes in a phase III trial. (The BMJ)

Use of artificial intelligence guidance did not improve the "resect-and-discard" strategy for , a meta-analysis of published studies showed. (Lancet Gastroenterology & Hepatology)

Singer Patti Scialfa, perhaps better known to many people as Mrs. Bruce Springsteen, recently disclosed that she has had since 2018. (CNN)

Caribbean women with had fewer children and started menstruation (menarche) at earlier ages, according to a study that added to evidence from previous studies. (Sylvester Comprehensive Cancer Center, JAMA Network Open)

New insights into and cancer risk among men. (Moffitt Cancer Center, Nature Microbiology)

Rigel Pharmaceuticals issued a Dear Health Care Provider letter advising clinicians of a newly identified in patients treated with pralsetinib (Gavreto).

Towa Pharmaceutical Europe issued a in the U.S. of the antidepressant/pain reliever duloxetine delayed-release capsules, after tests showed the medication contained unacceptable levels of cancer-causing nitrosamines. (Newsweek)

Observations and insights into the recent uptick in . (Foley & Lardner)

PMV Pharmaceuticals announced in a phase I trial of its p53-targeting drug rezatapopt plus pembrolizumab (Keytruda) in solid tumors because of dose-limiting toxicities and limited clinical benefit at the maximum tolerated dose.

A study of showed no effect on objectively measured postchemotherapy cognitive function but a significant association with patients' own perceptions of cognitive function. (Cancer)

A cancer specialist opens up about the . (Oncology News Central)

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    Charles Bankhead is senior editor for oncology and also covers urology, dermatology, and ophthalmology. He joined ֱ in 2007.