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Ethics Consult: Fertilize Human Egg With Neanderthal Sperm?

— You make the call

Last Updated November 18, 2022
MedpageToday
A photo of a Neanderthal mannequin wearing a modern suit and holding a stone age too.

Welcome to Ethics Consult -- an opportunity to discuss, debate (respectfully), and learn together. We select an ethical dilemma from a true, but anonymized, patient care case. You vote on your decision in the case and, next week, we'll reveal how you all made the call. Bioethicist Jacob M. Appel, MD, JD, will also weigh in with an ethical framework to help you learn and prepare.

The following case is adapted from Appel's 2019 book, .

Researchers in the Alps have discovered the remains of a Neanderthal frozen and preserved in glacial ice there. With the help of fertility specialists, they are able to extract DNA from the sperm of this preserved prehuman. Their hope is to infuse his DNA into Homo sapiens sperm and use that sperm cell to fertilize a human egg. They have already recruited a female scientist who is willing to attempt to bring such an embryo to term in her womb.

See the results and what an ethics expert has to say.

Jacob M. Appel, MD, JD, is director of ethics education in psychiatry and a member of the institutional review board at the Icahn School of Medicine at Mount Sinai in New York City. He holds an MD from Columbia University, a JD from Harvard Law School, and a bioethics MA from Albany Medical College.

Check out some of our past Ethics Consult cases:

Approve Experimental Head Transplant?

Agree to Perform Voluntary Surgical Castration?

Biopsy Kids' Brains Even Though They Won't Benefit?